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Forward RNAi screens in primary human hematopoietic stem/progenitor cells
The mechanisms regulating key fate decisions such as self-renewal and differentiation in hematopoietic stem and progenitor cells (HSPC) remain poorly understood. We report here a screening strategy developed to assess modulators of human hematopoiesis using a lentiviral short hairpin RNA (shRNA) lib...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670788/ https://ncbi.nlm.nih.gov/pubmed/19188664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-176396 |
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