Forward RNAi screens in primary human hematopoietic stem/progenitor cells

The mechanisms regulating key fate decisions such as self-renewal and differentiation in hematopoietic stem and progenitor cells (HSPC) remain poorly understood. We report here a screening strategy developed to assess modulators of human hematopoiesis using a lentiviral short hairpin RNA (shRNA) lib...

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Bibliografiske detaljer
Main Authors: Ali, Nicole, Karlsson, Christine, Aspling, Marie, Hu, Guang, Hacohen, Nir, Scadden, David T., Larsson, Jonas
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670788/
https://ncbi.nlm.nih.gov/pubmed/19188664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-176396
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