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Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle

There is clear evidence that the phenotypic modulation of smooth muscle cells (SMCs) contributes to the pathophysiology of vascular disease. Phenotypic modulation refers to the unique ability of SMCs to alter their phenotype in response to extracellular stimuli and is hallmarked by the loss of SMC m...

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Detalhes bibliográficos
Main Authors: Deaton, Rebecca A., Gan, Qiong, Owens, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670704/
https://ncbi.nlm.nih.gov/pubmed/19168719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01230.2008
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