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Interleukin-1β modulates smooth muscle cell phenotype to a distinct inflammatory state relative to PDGF-DD via NF-κB-dependent mechanisms

Smooth muscle cell (SMC) phenotypic modulation in atherosclerosis and in response to PDGF in vitro involves repression of differentiation marker genes and increases in SMC proliferation, migration, and matrix synthesis. However, SMCs within atherosclerotic plaques can also express a number of proinf...

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Detalhes bibliográficos
Main Authors: Alexander, Matthew R., Murgai, Meera, Moehle, Christopher W., Owens, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339851/
https://ncbi.nlm.nih.gov/pubmed/22318995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00160.2011
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