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Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle

There is clear evidence that the phenotypic modulation of smooth muscle cells (SMCs) contributes to the pathophysiology of vascular disease. Phenotypic modulation refers to the unique ability of SMCs to alter their phenotype in response to extracellular stimuli and is hallmarked by the loss of SMC m...

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Détails bibliographiques
Auteurs principaux: Deaton, Rebecca A., Gan, Qiong, Owens, Gary K.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670704/
https://ncbi.nlm.nih.gov/pubmed/19168719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01230.2008
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