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Dissociation between sensing and metabolism of glucose in sugar sensing neurones

Some of the neurones controlling sleep, appetite and hormone release act as specialized detectors of ambient glucose. Their sugar sensing is conventionally thought to involve glucokinase-dependent metabolism of glucose to ATP, which then alters membrane excitability by modulating ATP-dependent chann...

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Detalhes bibliográficos
Main Authors: Gonzàlez, J Antonio, Reimann, Frank, Burdakov, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670021/
https://ncbi.nlm.nih.gov/pubmed/18981030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163410
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