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Metabolism-Independent Sugar Sensing in Central Orexin Neurons

OBJECTIVE— Glucose sensing by specialized neurons of the hypothalamus is vital for normal energy balance. In many glucose-activated neurons, glucose metabolism is considered a critical step in glucose sensing, but whether glucose-inhibited neurons follow the same strategy is unclear. Orexin/hypocret...

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Detalhes bibliográficos
Main Authors: González, J. Antonio, Jensen, Lise T., Fugger, Lars, Burdakov, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551664/
https://ncbi.nlm.nih.gov/pubmed/18591392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0548
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