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Dissociation between sensing and metabolism of glucose in sugar sensing neurones

Some of the neurones controlling sleep, appetite and hormone release act as specialized detectors of ambient glucose. Their sugar sensing is conventionally thought to involve glucokinase-dependent metabolism of glucose to ATP, which then alters membrane excitability by modulating ATP-dependent chann...

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Detalles Bibliográficos
Main Authors: Gonzàlez, J Antonio, Reimann, Frank, Burdakov, Denis
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670021/
https://ncbi.nlm.nih.gov/pubmed/18981030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163410
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