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Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels
ABSTRACT: Central orexin/hypocretin neurons promote wakefulness, feeding and reward-seeking, and control blood glucose levels by regulating sympathetic outflow to the periphery. Glucose itself directly suppresses the electrical activity and cytosolic calcium levels of orexin cells. Recentin vitrostu...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249044/ https://ncbi.nlm.nih.gov/pubmed/22005675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.217000 |
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