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Influence of Antiretroviral Drugs on the Pharmacokinetics of Prednisolone in HIV-Infected Individuals

BACKGROUND: Corticosteroids are cytochrome P450 3A4 substrates, which have been associated with toxicities in patients receiving cytochrome P450 3A4 inhibitors such as human immunodeficiency virus protease inhibitors. In a study in healthy volunteers, ritonavir significantly increased prednisolone e...

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Hlavní autoři: Busse, Kristin H., Formentini, Elizabeth, Alfaro, Raul M., Kovacs, Joseph A., Penzak, Scott R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669927/
https://ncbi.nlm.nih.gov/pubmed/18645517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31817bebeb
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