Lack of sex-related differences in saquinavir pharmacokinetics in an HIV-seronegative cohort

AIMS: To examine the influence of sex on steady-state saquinavir pharmacokinetics in HIV-seronegative volunteers administered saquinavir without a concomitant protease inhibitor. METHODS: Thirty-eight healthy volunteers (14 female) received saquinavir soft-gel capsules 1200 mg three times daily for...

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Autores principales: Robertson, Sarah M, Formentini, Elizabeth, Alfaro, Raul M, Natarajan, Ven, Falloon, Judith, Penzak, Scott R
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2006
Materias:
Pharmacokinetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885032/
https://ncbi.nlm.nih.gov/pubmed/16542198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02593.x
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