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Limitations of Using a Single Postdose Midazolam Concentration to Predict CYP3A-Mediated Drug Interactions
Midazolam is a common probe used to predict CYP3A activity, but multiple blood samples are necessary to determine midazolam's area under the concentration-time curve (AUC). As such, single sampling strategies have been examined. The purpose of this study was to assess the ability of single mida...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658757/ https://ncbi.nlm.nih.gov/pubmed/18420532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270008317305 |
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