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Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products

The structures of complex polyketide natural products, such as erythromycin, are programmed by multifunctional polyketide synthases (PKSs) that contain modular arrangements of functional domains. The colinearity between the activities of modular PKS domains and structure of the polyketide product po...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McDaniel, Robert, Thamchaipenet, Arinthip, Gustafsson, Claes, Fu, Hong, Betlach, Melanie, Betlach, Mary, Ashley, Gary
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC26699/
https://ncbi.nlm.nih.gov/pubmed/10051557
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