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High-level Expression of Glycoprotein D by a Dominant-negative HSV-1 Virus Augments Its Efficacy as a Vaccine Against HSV-1 Infection
Using the T-REx™ (Invitrogen, CA) gene switch technology, we previously generated a dominant-negative HSV-1 recombinant, CJ83193, capable of inhibiting its own replication as well as that of wild-type HSV-1 and HSV-2. It has been further demonstrated that CJ83193 is an effective vaccine against HSV-...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669847/ https://ncbi.nlm.nih.gov/pubmed/19005489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.349 |
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