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Development of a Glycoprotein D-Expressing Dominant-Negative and Replication-Defective Herpes Simplex Virus 2 (HSV-2) Recombinant Viral Vaccine against HSV-2 Infection in Mice

Using the T-REx (Invitrogen, California) gene switch technology and a dominant-negative mutant polypeptide of herpes simplex virus 1 (HSV-1)-origin binding protein UL9, we previously constructed a glycoprotein D-expressing replication-defective and dominant-negative HSV-1 recombinant viral vaccine,...

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Detalhes bibliográficos
Main Authors: Akhrameyeva, Natalie V., Zhang, Pengwei, Sugiyama, Nao, Behar, Samuel M., Yao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126160/
https://ncbi.nlm.nih.gov/pubmed/21389121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02548-10
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