The Dominant-Negative Herpes Simplex Virus Type 1 (HSV-1) Recombinant CJ83193 Can Serve as an Effective Vaccine against Wild-Type HSV-1 Infection in Mice

By selectively regulating the expression of the trans-dominant-negative mutant polypeptide UL9-C535C, of herpes simplex virus type 1 (HSV-1) origin binding protein UL9 with the tetracycline repressor (tetR)-mediated gene switch, we recently generated a novel replication-defective and anti-HSV-specif...

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Detalhes bibliográficos
Main Authors: Augustinova, Hanka, Hoeller, Daniela, Yao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415800/
https://ncbi.nlm.nih.gov/pubmed/15140973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5756-5765.2004
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