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Development of a Regulatable Oncolytic Herpes Simplex Virus Type 1 Recombinant Virus for Tumor Therapy

Oncolytic viruses are genetically modified viruses that preferentially replicate in host cancer cells, leading to the production of new viruses and, ultimately, cell death. Currently, no oncolytic viruses that are able to kill only tumor cells while leaving normal cells intact are available. Using T...

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Main Authors: Yao, Feng, Murakami, Nao, Bleiziffer, Oliver, Zhang, Pengwei, Akhrameyeva, Natali V., Xu, Ximing, Brans, Richard
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916535/
https://ncbi.nlm.nih.gov/pubmed/20519407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00059-10
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