TRH Receptor Type 2 Deficient Mice are Euthyroid and Exhibit Increased Depression and Reduced Anxiety Phenotypes

Thyrotropin-releasing hormone (TRH) is a neuropeptide that initiates its effects in mice by interacting with two G protein-coupled receptors, TRH receptor type 1 (TRH-R1) and TRH receptor type 2 (TRH-R2). Two previous reports described the effects of deleting TRH-R1 in mice. TRH-R1 knockout mice exh...

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Detalhes bibliográficos
Main Authors: Sun, Yuhua, Zupan, Bojana, Raaka, Bruce M., Toth, Miklos, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669701/
https://ncbi.nlm.nih.gov/pubmed/19078951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.217
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