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Wild-Type Male Offspring of fmr-1(+/−) Mothers Exhibit Characteristics of the Fragile X Phenotype

Fragile X syndrome is an X-linked disorder caused by the inactivation of the FMR-1 gene with symptoms ranging from impaired cognitive functions to seizures, anxiety, sensory abnormalities, and hyperactivity. Males are more severely affected than heterozygote (H) females, who, as carriers, have a 50%...

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Autors principals: Zupan, Bojana, Toth, Miklos
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904748/
https://ncbi.nlm.nih.gov/pubmed/18172434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301651
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