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Wild-Type Male Offspring of fmr-1(+/−) Mothers Exhibit Characteristics of the Fragile X Phenotype
Fragile X syndrome is an X-linked disorder caused by the inactivation of the FMR-1 gene with symptoms ranging from impaired cognitive functions to seizures, anxiety, sensory abnormalities, and hyperactivity. Males are more severely affected than heterozygote (H) females, who, as carriers, have a 50%...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904748/ https://ncbi.nlm.nih.gov/pubmed/18172434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301651 |
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