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Inactivation of the maternal fragile X gene results in sensitization of GABA(B) receptor function in the offspring
Fragile X syndrome is an X linked disorder caused by the inactivation of the FMR-1 gene with symptoms ranging from impaired cognitive functions to seizures, anxiety, sensory abnormalities and hyperactivity. Although Fragile X syndrome is considered a typical Mendelian disorder, we have recently repo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666962/ https://ncbi.nlm.nih.gov/pubmed/18812493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143990 |
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