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Inactivation of the maternal fragile X gene results in sensitization of GABA(B) receptor function in the offspring

Fragile X syndrome is an X linked disorder caused by the inactivation of the FMR-1 gene with symptoms ranging from impaired cognitive functions to seizures, anxiety, sensory abnormalities and hyperactivity. Although Fragile X syndrome is considered a typical Mendelian disorder, we have recently repo...

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Main Authors: Zupan, Bojana, Toth, Miklos
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666962/
https://ncbi.nlm.nih.gov/pubmed/18812493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143990
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