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Short-Term Striatal Gene Expression Responses to Brain-Derived Neurotrophic Factor Are Dependent on MEK and ERK Activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is believed to be an important regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of BDNF delivery to the striatum has been implicated in the pathophysiology of Huntington's disease. Nevertheless, many...

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Main Authors: Gokce, Ozgun, Runne, Heike, Kuhn, Alexandre, Luthi-Carter, Ruth
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669182/
https://ncbi.nlm.nih.gov/pubmed/19390590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005292
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