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Short-Term Striatal Gene Expression Responses to Brain-Derived Neurotrophic Factor Are Dependent on MEK and ERK Activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is believed to be an important regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of BDNF delivery to the striatum has been implicated in the pathophysiology of Huntington's disease. Nevertheless, many...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gokce, Ozgun, Runne, Heike, Kuhn, Alexandre, Luthi-Carter, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669182/
https://ncbi.nlm.nih.gov/pubmed/19390590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005292
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