Microsatellite Instability Predicts Improved Response to Adjuvant Therapy With Irinotecan, Fluorouracil, and Leucovorin in Stage III Colon Cancer: Cancer and Leukemia Group B Protocol 89803

PURPOSE: Colon cancers exhibiting DNA mismatch repair (MMR) defects demonstrate distinct clinical and pathologic features, including better prognosis and reduced response to fluorouracil (FU) –based chemotherapy. This prospective study investigated adjuvant chemotherapy containing FU and irinotecan...

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Bibliografiset tiedot
Päätekijät: Bertagnolli, Monica M., Niedzwiecki, Donna, Compton, Carolyn C., Hahn, Hejin P., Hall, Margaret, Damas, Beatrice, Jewell, Scott D., Mayer, Robert J., Goldberg, Richard M., Saltz, Leonard B., Warren, Robert S., Redston, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2009
Aiheet:
Original Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668707/
https://ncbi.nlm.nih.gov/pubmed/19273709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.2071
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