p27(Kip1) in Stage III Colon Cancer: Implications for Outcome Following Adjuvant Chemotherapy in CALGB 89803

BACKGROUND: In retrospective studies, loss of p27(Kip1) (p27), a cyclin dependent kinase inhibitor, has been associated with poor prognosis following colorectal cancer treatment. In a prospective study, we validated this relationship in patients enrolled on a trial of adjuvant chemotherapy for Stage...

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Bibliografiske detaljer
Main Authors: Bertagnolli, Monica M., Warren, Robert S., Niedzwiecki, Donna, Mueller, Elke, Compton, Carolyn C., Redston, Mark, Hall, Margaret, Hahn, Hejin P., Jewell, Scott D., Mayer, Robert J., Goldberg, Richard M., Saltz, Leonard B., Loda, Massimo
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059545/
https://ncbi.nlm.nih.gov/pubmed/19276255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2674
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