Microsatellite Instability and Loss of Heterozygosity at Chromosomal Location 18q: Prospective Evaluation of Biomarkers for Stages II and III Colon Cancer—A Study of CALGB 9581 and 89803

PURPOSE: Colorectal cancer (CRC) develops as a result of a series of accumulated genomic changes that produce oncogene activation and tumor suppressor gene loss. These characteristics may classify CRC into subsets of distinct clinical behaviors. PATIENTS AND METHODS: We studied two of these genomic...

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Hauptverfasser: Bertagnolli, Monica M., Redston, Mark, Compton, Carolyn C., Niedzwiecki, Donna, Mayer, Robert J., Goldberg, Richard M., Colacchio, Thomas A., Saltz, Leonard B., Warren, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2011
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157981/
https://ncbi.nlm.nih.gov/pubmed/21747089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.0092
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