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Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1

In order to understand the impact of zidovudine resistance and thymidine analog mutations (TAMs) on subtype C human immunodeficiency virus type 1, we created mutants in subtype C reverse transcriptase (RT). The subtype B RT was placed in a subtype C backbone to act as a control. Mutants and wild-typ...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Armstrong, Kimberly L., Lee, Tun-Hou, Essex, M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668487/
https://ncbi.nlm.nih.gov/pubmed/19225005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02645-08
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