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Reduced Ribavirin Antiviral Efficacy via Nucleoside Transporter-Mediated Drug Resistance

Treatment for hepatitis C virus infection currently consists of pegylated interferon and ribavirin (RBV), a nucleoside analog. Although RBV clearly plays a role in aiding the treatment response, its antiviral mechanism is unclear. Regardless of the specific mechanism of RBV, we hypothesize that diff...

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Главные авторы: Ibarra, Kristie D., Pfeiffer, Julie K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668478/
https://ncbi.nlm.nih.gov/pubmed/19244331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02280-08
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