Mechanism of Antiviral Drug Resistance of Vaccinia Virus: Identification of Residues in the Viral DNA Polymerase Conferring Differential Resistance to Antipoxvirus Drugs

The acyclic nucleoside phosphonate (ANP) family of drugs shows promise as therapeutics for treating poxvirus infections. However, it has been questioned whether the utility of these compounds could be compromised through the intentional genetic modification of viral sequences by bioterrorists or the...

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Detaylı Bibliyografya
Asıl Yazarlar: Gammon, Don B., Snoeck, Robert, Fiten, Pierre, Krečmerová, Marcela, Holý, Antonín, De Clercq, Erik, Opdenakker, Ghislain, Evans, David H., Andrei, Graciela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593306/
https://ncbi.nlm.nih.gov/pubmed/18842735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01528-08
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