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ENT1, a Ribavirin Transporter, Plays a Pivotal Role in Antiviral Efficacy of Ribavirin in a Hepatitis C Virus Replication Cell System

We previously showed that equilibrative nucleoside transporter 1 (ENT1) is a primary ribavirin transporter in human hepatocytes. However, because the role of this transporter in the antiviral mechanism of the drug remains unclear, the present study aimed to elucidate the role of ENT1 in ribavirin an...

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Détails bibliographiques
Auteurs principaux: Iikura, Minami, Furihata, Tomomi, Mizuguchi, Misa, Nagai, Miki, Ikeda, Masanori, Kato, Nobuyuki, Tsubota, Akihito, Chiba, Kan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294941/
https://ncbi.nlm.nih.gov/pubmed/22232287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05762-11
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