Striking Species Difference in the Contribution of Concentrative Nucleoside Transporter 2 to Nucleoside Uptake between Mouse and Rat Hepatocytes

Concentrative nucleoside transporter 2 (CNT2) (encoded by the SLC28A2 gene) transports various antiviral or antitumor purine nucleoside analogs to be involved in their pharmacokinetics and pharmacological actions. The results of our study showed that mouse hepatocytes hardly expressed CNT2 mRNA and...

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Detalhes bibliográficos
Main Authors: Furihata, Tomomi, Fukuchi, Yukina, Iikura, Minami, Hashizume, Misato, Miyajima, Atsushi, Nagai, Miki, Chiba, Kan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897278/
https://ncbi.nlm.nih.gov/pubmed/20421393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00010-10
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