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The Rv1712 Locus from Mycobacterium tuberculosis H37Rv Codes for a Functional CMP Kinase That Preferentially Phosphorylates dCMP

The Mycobacterium tuberculosis cmk gene, predicted to encode a CMP kinase (CMK), was cloned and expressed, and its product was purified to homogeneity. Steady-state kinetics confirmed that M. tuberculosis CMK is a monomer that preferentially phosphorylates CMP and dCMP by a sequential mechanism. A p...

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Detalhes bibliográficos
Main Authors: Thum, Caroline, Schneider, Cristopher Z., Palma, Mario S., Santos, Diógenes S., Basso, Luiz A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668428/
https://ncbi.nlm.nih.gov/pubmed/19181797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01337-08
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