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The Effect of the Nonionic Block Copolymer Pluronic P85 on Gene Expression in Mouse Muscle and Antigen Presenting Cells

DNA vaccines can be greatly improved by polymer agents that simultaneously increase transgene expression and activate immunity. We describe here Pluronic P85 (P85), a triblock copolymer of ethylene oxide (EO) and propylene oxide (PO) EO(26)-PO(40)-EO(26),. Using a mouse model we demonstrate that co-...

詳細記述

保存先:
書誌詳細
主要な著者: Gaymalov, Zagit Z., Yang, Zhihui, Pisarev, Vladimir M., Alakhov, Valery Yu., Kabanov, Alexander V.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667955/
https://ncbi.nlm.nih.gov/pubmed/19064283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.10.064
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