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The Effect of the Nonionic Block Copolymer Pluronic P85 on Gene Expression in Mouse Muscle and Antigen Presenting Cells

DNA vaccines can be greatly improved by polymer agents that simultaneously increase transgene expression and activate immunity. We describe here Pluronic P85 (P85), a triblock copolymer of ethylene oxide (EO) and propylene oxide (PO) EO(26)-PO(40)-EO(26),. Using a mouse model we demonstrate that co-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gaymalov, Zagit Z., Yang, Zhihui, Pisarev, Vladimir M., Alakhov, Valery Yu., Kabanov, Alexander V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667955/
https://ncbi.nlm.nih.gov/pubmed/19064283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.10.064
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