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Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells
Pluronic block copolymer P85 (P85) sensitizes multidrug resistant (MDR) cancer cells resulting in the increase of cytotoxic activity of antineoplastic agents. This effect is attributed to the inhibition of the most clinically relevant drug efflux transporter, P-glycoprotein (Pgp), through the combin...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711210/ https://ncbi.nlm.nih.gov/pubmed/15939500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2005.03.019 |
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