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Prediction of BRCA Mutations Using the BRCAPRO Model in Clinic-Based African American, Hispanic, and Other Minority Families in the United States

PURPOSE: BRCAPRO, a BRCA mutation carrier prediction model, was developed on the basis of studies in individuals of Ashkenazi Jewish and European ancestry. We evaluated the performance of the BRCAPRO model among clinic-based minority families. We also assessed the clinical utility of mutation status...

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Detalhes bibliográficos
Main Authors: Huo, Dezheng, Senie, Ruby T., Daly, Mary, Buys, Saundra S., Cummings, Shelly, Ogutha, Jacqueline, Hope, Kisha, Olopade, Olufunmilayo I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667822/
https://ncbi.nlm.nih.gov/pubmed/19188678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.5869
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