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Novel germline PALB2 truncating mutations in African-American breast cancer patients
BACKGROUND: It has been demonstrated that PALB2 acts as a bridging molecule between the BRCA1 and BRCA2 proteins and is responsible for facilitating BRCA2-mediated DNA repair. Truncating mutations in the PALB2 gene have been reported to be enriched in Fanconi anemia and breast cancer patients in var...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244533/ https://ncbi.nlm.nih.gov/pubmed/21932393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26388 |
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