c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells

BACKGROUND: The BRCA1 gene plays an important role in the maintenance of genomic stability. BRCA1 inactivation contributes to breast cancer tumorigenesis. An increasing number of transcription factors have been shown to regulate BRCA1 expression. c-Myc can act as a transcriptional activator, regulat...

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Autori principali: Chen, Yinghua, Xu, Jinhua, Borowicz, Stanley, Collins, Cindy, Huo, Dezheng, Olopade, Olufunmilayo I
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141769/
https://ncbi.nlm.nih.gov/pubmed/21668996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-246
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