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Contribution of IRF-3 Mediated IFNβ Production to DNA Vaccine Dependent Cellular Immune Responses
The mechanism(s) by which DNA vaccines activate Ag-specific cellular immune responses is incompletely understood. Current findings indicate that IRF-3 plays an important role in this process. The IRF-3 dependent signaling pathway is triggered by the presence of intracytoplasmic DNA, and culminates i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667800/ https://ncbi.nlm.nih.gov/pubmed/19356618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.01.134 |
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