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IRF7-dependent IFNβ production in response to RANKL promotes medullary thymic epithelial cell development
The contributions of IRF3/7 and the type I interferons IFNα/β to the innate host defense have been extensively investigated, however, their role in thymic development is less clear. Here we show that mice lacking the type I interferon receptor IFNAR or the downstream transcription factor STAT1 harbo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608802/ https://ncbi.nlm.nih.gov/pubmed/23440417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203086 |
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