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Recent progress concerning CpG DNA and its use as a vaccine adjuvant
CpG Oligonucleotides (ODN) are immunomodulatory synthetic oligonucleotides designed to specifically agonize Toll-like receptor 9. Here, we review recent progress in understanding the mechanism of action of CpG ODN and provide an overview of human clinical trial results using CpG ODN to improve the v...
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| Udgivet i: | Expert Rev Vaccines |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335645/ https://ncbi.nlm.nih.gov/pubmed/24308579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2014.863715 |
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