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Recent progress concerning CpG DNA and its use as a vaccine adjuvant

CpG Oligonucleotides (ODN) are immunomodulatory synthetic oligonucleotides designed to specifically agonize Toll-like receptor 9. Here, we review recent progress in understanding the mechanism of action of CpG ODN and provide an overview of human clinical trial results using CpG ODN to improve the v...

詳細記述

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書誌詳細
出版年:Expert Rev Vaccines
主要な著者: Shirota, Hidekazu, Klinman, Dennis M
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335645/
https://ncbi.nlm.nih.gov/pubmed/24308579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2014.863715
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