Characterization of the Structural Features and Interactions of Sclerostin: MOLECULAR INSIGHT INTO A KEY REGULATOR OF Wnt-MEDIATED BONE FORMATION

The secreted glycoprotein sclerostin has recently emerged as a key negative regulator of Wnt signaling in bone and has stimulated considerable interest as a potential target for therapeutics designed to treat conditions associated with low bone mass, such as osteoporosis. We have determined the stru...

詳細記述

保存先:
書誌詳細
主要な著者: Veverka, Vaclav, Henry, Alistair J., Slocombe, Patrick M., Ventom, Andrew, Mulloy, Barbara, Muskett, Frederick W., Muzylak, Mariusz, Greenslade, Kevin, Moore, Adrian, Zhang, Li, Gong, Jianhua, Qian, Xueming, Paszty, Chris, Taylor, Richard J., Robinson, Martyn K., Carr, Mark D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
Protein Structure and Folding
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667775/
https://ncbi.nlm.nih.gov/pubmed/19208630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807994200
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料