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Unidirectional Binding of Clostridial Collagenase to Triple Helical Substrates
Histotoxic clostridia produce collagenases responsible for extensive tissue destruction in gas gangrene. The C-terminal collagen-binding domain (CBD) of these enzymes is the minimal segment required to bind to collagen fibril. Collagen binding efficiency of CBD is more pronounced in the presence of...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667773/ https://ncbi.nlm.nih.gov/pubmed/19208618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807684200 |
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