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Bacterial collagen-binding domain targets undertwisted regions of collagen
Clostridium histolyticum collagenase causes extensive degradation of collagen in connective tissue that results in gas gangrene. The C-terminal collagen-binding domain (CBD) of these enzymes is the minimal segment required to bind to a collagen fibril. CBD binds unidirectionally to the undertwisted...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526996/ https://ncbi.nlm.nih.gov/pubmed/22898990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2145 |
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