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Ca(2+) induced linker transformation leads to compact and rigid collagen binding domain of Clostridium histolyticum collagenase
CLOSTRIDIUM HISTOLYTICUM: collagenase is responsible for extensive tissue destruction in gas gangrene, and its activity is enhanced by calcium ions. Collagen binding domain (CBD) is the minimal segment of the enzyme needed for binding to insoluble collagen fibrils and for subsequent collagenolysis....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782454/ https://ncbi.nlm.nih.gov/pubmed/19490118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07078.x |
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