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Ca(2+) induced linker transformation leads to compact and rigid collagen binding domain of Clostridium histolyticum collagenase

CLOSTRIDIUM HISTOLYTICUM: collagenase is responsible for extensive tissue destruction in gas gangrene, and its activity is enhanced by calcium ions. Collagen binding domain (CBD) is the minimal segment of the enzyme needed for binding to insoluble collagen fibrils and for subsequent collagenolysis....

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Detalhes bibliográficos
Main Authors: Philominathan, Sagaya Theresa Leena, Matsushita, Osamu, Gensure, Robert, Sakon, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782454/
https://ncbi.nlm.nih.gov/pubmed/19490118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07078.x
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