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The CREB Coactivator TORC1 is Required for Energy Balance and Fertility
Obesity is a major risk factor in the development of insulin resistance and Type 2 diabetes. Under lean conditions, the adipocyte-derived hormone leptin maintains energy balance by acting on hypothalamic leptin receptors (LRbs) that trigger activation of the JAK2/STAT3 pathway 1–4. Although disrupti...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667698/ https://ncbi.nlm.nih.gov/pubmed/18758446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1866 |
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