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High-content Functional Screen to Identify Proteins that Correct F508del-CFTR Function
Cystic Fibrosis is caused by mutations in CFTR, with a deletion of a phenylalanine at position 508 (F508del-CFTR) representing the most common mutation. The F508del-CFTR protein exhibits a trafficking defect and is retained in the endoplasmic reticulum. Here we describe the development of a high-con...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667356/ https://ncbi.nlm.nih.gov/pubmed/19088066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800268-MCP200 |
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