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Generation of Oxygen Deficiency in Cell Culture Using a Two-Enzyme System to Evaluate Agents Targeting Hypoxic Tumor Cells
The poor and aberrant vascularization of solid tumors makes them susceptible to localized areas of oxygen deficiency that can be considered sites of tumor vulnerability to pro-drugs that are preferentially activated to cytotoxic species under conditions of low oxygenation. To readily facilitate the...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667281/ https://ncbi.nlm.nih.gov/pubmed/18959466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1431.1 |
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