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Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation
Splicing requires reversible phosphorylation of serine/arginine-rich (SR) proteins, which direct splice site selection in eukaryotic mRNA. These phosphorylation events are dependent on SR protein (SRPK) and cdc2-like kinase (CLK) families. SRPK1 phosphorylation of splicing factors is restricted by a...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cell Press
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667211/ https://ncbi.nlm.nih.gov/pubmed/19278650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.12.023 |
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